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Home / Drugs / Starting with A / Aceprometazine 		 
Aceprometazine
  

Aceprometazine (INN) is a prescription drug with neuroleptic and anti-histamine properties. It is not widely prescribed. It may be used in combination with meprobamate for the treatment of sleep disorders. This combination is available in France under the trade name Mepronizine. [Wikipedia]
BrandsMepronizine
CategoriesAntihistamines
Sedatives and Hypnotics
Synonyms10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone
Aceprometazina [inn-spanish]
Aceprometazinum [inn-latin]
Acepromethazine

indication

Aceprometazine is often used in combination with meprobamate for the treatment of sleep disorders.

pharmacology

Aceprometazine is a drug with neuroleptic and anti-histamine properties. It is not widely prescribed.

mechanism of action

Aceprometazine, acting as an H1-receptor antagonist can induce sedation by being able to cross the blood-brain-barrier and binding to H1-receptors in the central nervous system.

biotransformation

Hepatic.

absorption

Rapidly absorbed following oral administration.

drug interactions

Donepezil: Possible antagonism of action

Galantamine: Possible antagonism of action

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