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Home / Drugs / Starting with A / Adenosine triphosphate
 
Adenosine triphosphate
 

An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. [PubChem]
BrandsAdephos
Adetol
Adynol
Atipi
Atriphos
Cardenosine
Fosfobion
Glucobasin
Myotriphos
Phosphobion
Striadyne
Triadenyl
Triphosphaden
CategoriesDietary supplement
Micronutrient
Synonyms5'-ATP
Adenosine 5'-triphosphate
Adenosine 5'-triphosphoric acid
Adenosine-5'-triphosphate
Adenosine, 5'-(tetrahydrogen triphosphate)
Adenylpyrophosphoric acid
ATP
Triphosphoric acid adenosine ester

indication

For nutritional supplementation, also for treating dietary shortage or imbalance

pharmacology

Adenosine triphosphate (ATP) is the nucleotide known in biochemistry as the "molecular currency" of intracellular energy transfer; that is, ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis.

mechanism of action

ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cellular processes, most typically in mitochondria by oxidative phosphorylation under the catalytic influence of ATP synthase. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis.

toxicity

Oral LD50 in rats is > 2 g/kg.