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Home / Drugs / Starting with C / Chlophedianol
 
Chlophedianol
 

Chlophedianol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
BrandsCalmotusin
Coldrin
Dencyl
Detigon
Eutus
Tussistop
Ulo
Ulone
CategoriesAnesthetics, Local
Antihistamines
Antitussive Agents
Manufacturers3m pharmaceuticals inc
Synonyms1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenyl-1-propanol
1-Phenyl-1-(o-chlorophenyl)-3-dimethylaminopropanol
2-Chloro-alpha-(2-(dimethylamino)ethyl)benzhydrol
Alpha-(dimethylaminoethyl)-o-chlorobenzhydrol
Chlofedanol
Clofedano
Clofedanol
Clofedanolum [inn-latin]
Clofedianolo [italian]
Clophedianol base

indication

Used in the treatment of dry cough.

pharmacology

Chlophedianol (or Clofedanol) is a centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.

mechanism of action

Suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain.

biotransformation

Hepatic.