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Home / Drugs / Starting with C / Clioquinol
 
Clioquinol
 

Clioquinol was withdrawn in 1983 due to neurotoxicity.
BrandsAla-quin
Alchloquin
Alioform
Amebil
Amoenol
Bactol
Barquinol
Budoform
Chinoform
Chinoformum
Chlorojodochin
Cifoform
Cliochinolum
Cliquinol
Corque
Cortin
Cremo-quin
Dermaform
Dioquinol
Domeform
Eczecidin
Emaform
Enteritan
Entero-bio form
Entero-bioform
Entero-septol
Entero-vioform
Entero-vioformio
Enteroquinol
Enteroseptol
Enterovalodon
Enterozol
Enterseptol
Enterum locorten
Entrokin
Hi-eneterol
Hi-enterol
Hydriodide-enterol
Iodenterol
Iodoenterol
Lekosept
Loquinol
Mycoquin
Nioform
Oralcer
Quin-o-creme
Quinambicide
Quinoform
Rheaform
Rometin
Uad lotion
CategoriesAntifungal Agents
Synonyms5-Chlor-7-jod-8-hydroxy-chinolin [German]
5-Chloro-7-iodo-8-hydroxyquinoline
5-Chloro-7-iodo-8-quinolinol
5-Chloro-7-iodoquinolin-8-ol
5-Chloro-8-hydroxy-7-iodoquinoline
7-Iodo-5-chloro-8-hydroxyquinoline
7-Iodo-5-chloroxine
Caswell No. 193
Chloro-8-hydroxyiodoquinoline
Chloroiodoquin
Chloroiodoquine
Cliochinolo [dcit]
Clioquinolum [inn-latin]
IODO
Iodochlorhydroxyquin
Iodochlorhydroxyquinol
Iodochlorhydroxyquinoline
Iodochlorohydroxyquin
Iodochlorohydroxyquinoline
Iodochloroquine
Iodochloroxine
Iodochloroxychinolinum
Iodochloroxyquinoline
Iodoxyquinoline
Jodchloroxychinolinum

indication

Used as a topical antifungal treatment.

pharmacology

Clioquinol is a broad-spectrum antibacterial with antifungal properties. Application of clioquinol to extensive or eroded areas of the skin may lead to increased protein-bound iodine (PBI) levels within 1 week. In addition, elevated PBI levels may occur when relatively small areas of the skin are treated with clioquinol for more than 1 week.

mechanism of action

Clioquinol is bacteriostatic, however, the precise mechanism of its action is unknown.

absorption

Topical absorption is rapid and extensive, especially when the skin is covered with an occlusive dressing or if the medication is applied to extensive or eroded areas of the skin. Clioquinol is absorbed through the skin in sufficient amounts to affect thyroid function tests.