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Home / Drugs / Starting with C / Cycloleucine 		 
Cycloleucine
  

Cycloleucine is an amino acid formed by cyclization of leucine. Cycloleucine is a non-metabolisable amino acid and is a specific and reversible inhibitor of nucleic acid methylation, and as such is widely used in biochemical experiments. [Wikipedia]
CategoriesAntineoplastic Agents
Immunosuppressive Agents
Synonyms1-Amino-1-cyclopentanecarboxylic acid
1-Amino-cyclopentanecarboxylic acid
1-Aminocyclopentane-1-carboxylic acid
1-Aminocyclopentanecarboxylate
1-Aminocyclopentanecarboxylic acid
Amino-1-cyclopentanecarboxylic acid
Cyclo-leucine
Cycloleucin

pharmacology

Cycloleucine has cytostatic, immunosuppressive and antineoplastic activities.

toxicity

Oral, mouse: LD50 = 309 mg/kg; oral, rat: LD50 = 290 mg/kg

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