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Home / Drugs / Starting with E / Etorphine
 
Etorphine
 

A narcotic analgesic morphinan used as a sedative in veterinary practice. In Hong Kong, Etorphine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. It can only be used legally by health professionals and for university research purposes. The substance can be given by pharmacists under a prescription. In the US, Etorphine is listed as a Schedule I drug, although Etorphine hydrochloride is classified as Schedule II.
BrandsImmobilon
CategoriesHypnotics and Sedatives
Narcotics
Analgesics, Opioid
Synonyms19-Propylorvinol
7-alpha-Etorphine
DEA No. 9056
Etorphine HCl
Etorphine Hydrochloride
Etorphinum [INN-Latin]
M99

pharmacology

Etorphine is a synthetic cousin of morphine and 40,000 times more powerful. It can be produced from thebaine. It is most often used to immobilize elephants and other large mammals. Etorphine is only available legally for veterinary use and is strictly governed by law.

mechanism of action

Etorphine is an agonist at mu, delta, and kappa opioid receptors. It also has a weak affinity for the ORL1 nociceptin/orphanin FQ receptor.