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Home / Drugs / Starting with F / Fleroxacin 		 
Fleroxacin
  

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.
CategoriesAnti-Infective Agents
Anti-Infectives
Quinolones
Nucleic Acid Synthesis Inhibitors
SynonymsFleroxacin (jan/usan/inn)
Fleroxacin [usan:ban:inn:jan]
Fleroxacine
Fleroxacine [french]
Fleroxacino [spanish]
Fleroxacinum [latin]
Fleroxicin
FLRX
Megalocin
Megalocin (TN)
Megalone
Megalone (TN)
Megalosin
Quinodis
UNII-N804LDH51K

indication

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone.

pharmacology

Fleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.

mechanism of action

The inhibition of DNA gyrase and DNA topoisomerase 2 leads ultimately to cell death as these enzymes are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination.

absorption

Rapidly and well absorbed from the gastrointestinal tract after oral administration.

Terms of Use