Niflumic Acid | Genelabs.com

An analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. [PubChem]
Brands	Actol Flogovital Forenol Landruma Niflam Nifluril
Categories	Cyclooxygenase Inhibitors
Synonyms	2-(3-(Trifluoromethyl)-phenyl)aminonicotinic acid 2-(3-(Trifluoromethyl)anilino)nicotinic acid 2-(3-Trifluoromethyl-phenylamino)-nicotinic acid 2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid 2-[(3-Trifluoromethyl)Phenyl]Amino-3-Pyridine-Carboxylic Acid 2-[3-(Trifluoromethyl)anilino]nicotinic acid Acide niflumique [inn-french] Acido niflumico [inn-spanish] Acidum niflumicum [inn-latin] Lopac-N-0630 NFL Niflumate Nifluminic acid

Used in the treatment of rheumatoid arthritis.

Niflumic acid, a nonsteroidal anti-inflammatory fenamate, is a Ca²⁺-activated Cl^- channel blocker.

Niflumic acid is able to inhibit both phospholipase A2 as well as COX-2, thereby acting as an antiinflamatory and pain reduction agent.

Oral, mouse: LD₅₀ = 350 mg/kg; Oral, rat: LD₅₀ = 250 mg/kg

Hepatic.

Well absorbed following oral administration.

2.5 hours

Drugs database

	Drugs A-Z Brands A-Z Drugs by categories Drugs by manufacturer Drugs by packager Antibiotics for sale Online Viagra bestellen in Nederland