Phensuximide | Genelabs.com

Phensuximide is an anticonvulsant in the succinimide class. It suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.
Brands	(+/-)-N-Methyl-2-phenylsuccinimide 1-Methyl-3-Phenylsuccinimide Epimid Fenosuccimide Fensuccimide [DCIT] Fensuximida [INN-Spanish] Lifene Methylphenylsuccinimide Milontin Milontin (TN) Milonton Mirontin Mirotin;7 Phenosuccimide N-Methyl-2-phenylsuccinimide N-Methyl-alpha-phenolsuccinimide N-Methyl-alpha-phenylsuccinimide Phensuximid Phensuximide (USP) Phensuximide [BAN:INN] Phensuximidum [INN-Latin] Phenylsuximide Succinimide, N-methyl-2-phenyl- Succitimal
Categories	Anticonvulsants Antiepileptic Agents
Manufacturers	Parke davis div warner lambert co

indication

For the treatment of epilepsy.

pharmacology

Phensuximide suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.

mechanism of action

Phensuximide's mechanism of action not understood, but may act in inhibitory neuronal systems that are important in the generation of the three per second rhythm. It's effects may be related to its ability to inhibit depolarization-induced accumulation of cyclic AMP and cyclic GMP in brain tissue.

biotransformation

Hepatic.

absorption

Rapid and complete.

Drugs database

	Drugs A-Z Brands A-Z Drugs by categories Drugs by manufacturer Drugs by packager Antibiotics for sale Online Viagra bestellen in Nederland