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Home / Drugs / Starting with R / Rolicyclidine
 
Rolicyclidine
 

Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects. Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.
CategoriesHallucinogens
Synonyms1-(1-phenylcyclohexyl)pyrrolidine
DEA No. 7458
PCPy
Pyrrolidine analog of phencyclidine
Roliciclidina [INN-Spanish]
Rolicyclidinum [INN-Latin]

indication

Rolicyclidine has anesthetic properties and can induce a sedative effect.

pharmacology

Rolicyclidine is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects. Instead it acts by inducing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.

mechanism of action

Rolicyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor.