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Home / Drugs / Starting with S / Sermorelin 		 
Sermorelin
  

Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone (GHRH or GRF) consisting of 44 amino acid residues
BrandsGeref
CategoriesAnabolic Agents
Hormone Replacement Agents
ManufacturersEmd serono inc
PackagersChengdu Shengnuo Bio Pharmaceutical Co. Ltd.
Letco Medical Inc.
Live Well Drugstore LLC

indication

For the treatment of dwarfism, prevention of HIV-induced weight loss

pharmacology

Sermorelin is used in the treatment of children with growth hormone deficiency or growth failure. Geref increases plasma growth hormone (GH) concentration by stimulating the pituitary gland to release GH. Geref is similar to the full-length native hormone (44 residues) in its ability to stimulate GH secretion in humans.

mechanism of action

Sermorelin binds to the growth hormone releasing hormone receptor and mimics native GRF in its ability to stimulate growth hormone secretion.

half life

11-12 min

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